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ABOUT UPSTREAM
Upstream Biosciences Inc.
is a biotechnology company, founded in 2004. We discover, develop, and license genetic based diagnostics for cancer susceptibility and drug response. Our proprietary data mining pipeline enables us to locate and analyze genetic variations in the regions of DNA ‘upstream’ of the gene, the ‘gene switches,’ which control the quantities and timing of expression of the genes and proteins important to disease and drug response.

Our initial candidate genetic predisposition markers are targeted against liver, prostate, ovarian and thyroid cancer with a market potential of over one billion dollars and can complement existing detection tests.

Upstream’s proprietary data mining pipeline and assay generate candidate genetic biomarkers.

OUR MANAGEMENT TEAM:

Upstream's management team has over thirty years of combined experience in the biotech sector.

Joel Bellenson, CEO & Director
Dexster Smith, President & Director
Tim Fernback
, CFO

Founded Market Leading Companies:

  • Pangea Systems/DoubleTwist, (1991) leading bioinformatics product development firm
  • DigiScents, (1999) pioneered digital scent synthesis

Created Market Defining Products:

  • Incyte Pharmaceuticals’ LifeSeq, First Gene Expression Analysis Database, $1B revenue
  • Oxford GlycoSciences’ Rosetta, First Proteomics system
  • DoubleTwist’s GeneWorld, 40 pharma customers
  • First to Assemble Human Genome

Track-record of Successful Fundraising:

  • Previous companies’ raised ~ US$100M from leading venture capitalists in North America and Asia

Joel Lloyd Bellenson, Co-founder, Chairman, CEO & Director was the co-founder and CEO of DoubleTwist, formerly the world's leading bioinformatics company. Bellenson was also Co-founder and CEO of DigiScents, internationally known for sequencing and using the human olfactory receptors to digitize the sense of smell.  Bellenson is a graduate of Stanford University, where he studied molecular biology and international relations. He co-founded and managed the high-throughput DNA Analysis Facility at Stanford University Medical Center from 1989 to 1993 under Nobel Prize laureate Dr. Paul Berg. Bellenson wrote the bioinformatics chapter to the groundbreaking 1998 book, “DNA Microarrays, a Practical Approach,” Schena, et.al.

Dexster L. Smith, Co-founder, President & Director was co-founder and President of DoubleTwist, formerly the world's leading bioinformatics company. Smith was also Co-founder and President of DigiScents, internationally known for sequencing and using the human olfactory receptors to digitize the sense of smell. Smith is a graduate of Stanford University, where he studied industrial engineering and computer science.

Tim FernbackTim Fernback: CFO, has over a decade of experience financing both private and public companies in Canada. Mr. Fernback was the head of the technology consulting practice for Discovery Capital Corporation, a prominent British Columbia venture capital firm specializing in financing and consulting to technology based start-up ventures, and later ran the Investment Banking/ Corporate Finance Departments for the oldest and most respected Western Canadian based brokerage firm, Wolverton Securities Ltd.

In 2004, Mr. Fernback left Wolverton Securities and was the founder of a boutique technology consulting practice. Since 2002, Mr. Fernback has been an active director of the Okanagan Capital Fund, an Okanagan-based technology venture fund. Mr. Fernback is a graduate of McMaster University, where he studied molecular biology and biochemistry, and also a graduate of the University of British Columbia, where he completed his MBA with a concentration in Finance.

At Upstream Biosciences Inc., Mr. Fernback is responsible for directing, identifying and evaluating strategic financing and partnering opportunities for the Company. Mr. Fernback contributes to the establishment of the overall business support by working closely with the senior management team.