PATENTS

Upstream has filed seven (7) provisional patents and has a proprietary discovery pipeline that the Company would like to see generate a stream of intellectual property.

1. Method for combining 3D quantitative chemical structure activity relationships of compounds with genetic variation of drug targets and metabolic enzymes to optimize efficacy, provide predictive toxicology, and address drug resistant microorganisms.

2. Anti-parasitic compounds and methods for selection thereof.

3. Drug Response Diagnostics
A novel test for predicting the impact of genetic variations on patient drug reaction.

4. Liver Cancer Susceptibility Test
Genetic variations that determine a patients’ risk of getting liver cancer.

5. Prostate Cancer Susceptibility Test
Genetic variations that determine a patients’ risk of getting prostate cancer.

6. Ovarian Cancer Susceptibility Test
Genetic variations that determine a patients’ risk of getting ovarian cancer.

7. Thyroid Cancer Susceptibility Test
Genetic variations that determine a patients’ risk of getting thyroid cancer.